Image
|
Figure Caption
Fig. S5 Comparison of ROL, RAL and RA teratogenicity from treatments beginning at the shield stage.
(A-I) Embryos at 48 hpf that were treated from shield stage through 24 hpf with DMSO, ROL, RAL, and RA. (D,G) Low concentrations of RAL (0.1 µM) and ROL (10 µM) did not cause significant overt defects. (B,E,H) Intermediate concentrations of RAL (1 µM) and ROL (20 µM) and the lower concentration of RA (0.025 µM) produced truncated embryos that still had eyes (arrows). (C,F,I) 0.05 µM RA, 2 µM RAL, and 40 µM ROL produced severely truncated embryos with reduced eyes.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ PLoS One