Fig. S4 Lack of significant changes of neutrophil numbers under various experimental conditions. To support the specific changes of neutrophil numbers in the livers in various experimental conditions, the number of neutrophils were quantitated in the trunk region (somites 1-4). (A) Representative images of neutrophil distribution in the trunk of kras+ and kras- zebrafish larvae under various experimental conditions (from left to right), Control with doxycycline alone, FPR-A14 with doxycycline, PR39 with doxycycline, SB431542 with doxycycline, Mock injected, and Tgf-β depletion. (B) Quantification of numbers of neutrophils per somite among different treatment groups. (n=5 fish). NS, no significant difference.
Reprinted from Journal of hepatology, 63(2), Yan, C., Huo, X., Wang, S., Feng, Y., Gong, Z., Stimulation of hepatocarcinogenesis by neutrophils upon induction of oncogenic kras expression in transgenic zebrafish, 420-8, Copyright (2015) with permission from Elsevier. Full text @ J. Hepatol.