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Fig. S2 Biallelic disruption of tyrosinase, chordin and fgf-24 by CRISPR/Cas9. Two targets were co-injected with Cas9 in the cell of 1-cell stage of embryos and the phenotypes were observed within 5 days of development. Lateral views (A-B) and Dorsal view (C) of the wild-type embryos. (D) tyrosinase CRISPR-injected embryos showed reduced pigmentation, (E) chordin CRISPR-injected embryos showed dorsalization of ventral tissues and (F) fgf24 embryos showed lack of pectoral fins.
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Full text @ Genome Res.