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Fig. 6
Rapid downregulation of anterior neural genes by gbx2 induction at the bud stage. Offspring embryos from crosses between wild-type fish and hsp70l:gbx2+/– Tg fish were exposed to heat shock at the bud stage and examined immediately (0 h) or 1 h and 2 h later for the expression of brain regional genes shown at the top. Reduced expression is shown only when it was observed. The proportions of the defects and total numbers of scored embryos are shown in the respective panels. Dorsal views with anterior to the top. Scale bar, 200 µm.
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Reprinted from Mechanisms of Development, 130(11-12), Nakayama, Y., Kikuta, H., Kanai, M., Yoshikawa, K., Kawamura, A., Kobayashi, K., Wang, Z., Khan, A., Kawakami, K., and Yamasu, K., Gbx2 functions as a transcriptional repressor to regulate the specification and morphogenesis of the mid-hindbrain junction in a dosage- and stage-dependent manner, 532-52, Copyright (2013) with permission from Elsevier. Full text @ Mech. Dev.