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Fig. 6 Eomesa negatively regulates neural marker gene expression. (A) ChIP-seq data showing binding of Eomesa at sphere stage proximal to neural marker genes; scale in reads per million reads. (B)In situ hybridisation of wild type and MZeomesa mutant embryos for stm, tfap2a, vgll4l and zic3 showing upregulation of these genes (lateral view, animal to the top). (C)In situ hybridisation of control injected and eomesa injected embryos for stm, tfap2a, vgll4l and zic3 showing downregulation of these genes (lateral view, animal to the top). ChIP, chromatin immunoprecipitation sequencing.
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Full text @ BMC Biol.