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Fig. S3 SU5402 efficiently down-regulates FGF target genes etv4 and dusp6. Expression of the FGF-responsive genes etv4 (A, n = 12) and dusp6 (E, n = 6) is normal in embryos treated with DMSO from 18S to 26 hpf, but lost in embryos treated with 5 µM (B, n = 10; F, n = 8), 10 µM (C, n = 12; G, n = 10) and 15 µM (D, n = 9; H, n = 12) from 18S to 26 hpf. Inserts show the otic vesicle at higher magnification. All panels are lateral views with anterior to the left. Scale bars: 50 µm.
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