ZFIN Image: Dranow et al., 2013, Fig. 1

Image

Figure Caption

Fig. 1 Phenotypic sex reversal of nanos3^-/- 1° females correlates with loss of oocytes. (A-A′′) Representative 2.5 month old (mo) nanos3^+/- female control. (B-B′′) nanos3^-/- 1° female with large, egg-filled abdomen and light yellow fin pigmentation characteristic of control females. (C-C′′) Representative 5 mo nanos3^-/- 1° female. (D-D′′) Representative 5 mo nanos3^+/- male control. (E-E′′) Representative 5 mo nanos3^+/- female. At 5 mo, nanos3^-/- 1° females (C) have slim bodies and darker yellow fin pigmentation characteristic of control males (D). (A-E) Low magnification pictures showing anterior body. (A′-E′) Higher magnification picture showing anal fin. (A′′-E′′) magnified view of regions boxed in A′-E′. See also Fig. S1.

Acknowledgments

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Reprinted from Developmental Biology, 376(1), Dranow, D.B., Tucker, R.P., and Draper, B.W., Germ cells are required to maintain a stable sexual phenotype in adult zebrafish, 43-50, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.