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Fig. 1
Tumor angiogenesis in transgenic Tg(flk1:GFP) zebrafish embryos. Lateral view of a fluorescent transgenic Tg(flk1:GFP) zebrafish embryo at 1 dpf that was just transplanted with cancer cells labeled with red fluorescent dye (A); (B) shows a sketch depicting the SIV (in green) of a 3 day old zebrafish embryo; Lateral views of transgenic Tg(flk1:GFP) zebrafish embryos at 3 dpf transplanted with 3T3-L1 cells (negative control) (C), CL13 (D) and H1299 (E) cancer cells; White arrows (D, E) indicate newly formed ectopic vessels from the SIV. Scale bars = 100 μm.
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