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Fig. 8
Nom1-induced pancreas defect is p53 independent.
(A–D) Lateral views, anterior to the left. (A) control group at 3 dpf. (B) dg5 mutant group at 3 dpf. (C) Failure to rescue the pancreas defect by injection of 4 ng p53MO into dg5 mutant or (D) injection of nom1 MO in p53M214K mutant. (E) Expression of p53 and its targets Δ1113p53 and p21 are increased in dg5nom1 mutant, as assessed by quantitative PCR. Error bars mean±SD. **P<0.01, *P<0.05.
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