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Fig. 1

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ZDB-IMAGE-140723-61
Publication
DuVal et al., 2014 - Growth differentiation factor 6 as a putative risk factor in neuromuscular degeneration
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Figures for DuVal et al., 2014
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Fig. 1

Zebrafish harboring homozygous mutations in gdf6 can be raised to adulthood and do not display overt skeletal defects.

A. gdf6-/- fish are viable into adulthood, exhibit variably penetrant microphthalmia and normal body morphology. B. gdf6-/- fish exhibit somewhat decreased survival compared to gdf6+/+ siblings (n = 11 gdf6-/- fish; n = 4 gdf6+/+ siblings). C, D. gdf6-/- fish lack overt skeletal phenotypes, as revealed by (C) clearing and staining or by (D) microCT analysis. The latter is further represented as Supplemental Movie S1. Scale bars are 5 mm. A variety of fin morphologies were present in the fish examined, but these were neither different between experimental groups (genotypes) nor a significant covariant with swim performance (see Results).

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This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One
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