ZFIN Image: Walsh et al., 2011, Fig. 3

Image

Figure Caption

Fig. 3 Nhsl1b interacts genetically and physically with Scrib in the regulation of facial branchiomotor (FBM) neuron migration. (A,B) Wild-type (A) and double heterozygous nhsl1b^fh131/+; scrib^rw468/+ zebrafish embryos (B) at 48 hours post-fertilization (hpf). Double heterozygotes have unmigrated FBM neurons in rhombomere (r)4, indicative of a strong genetic interaction between the two genes. (C) Histogram of phenotypes in the genotypic classes arising from a nhsl1b^fh131/+ x scrib^rw468/+ cross. (D-G) Nhsl1b associates with Scrib and Psd95 (Dlg4). cDNA constructs were transfected into HEK293T cells as indicated. Whole cell lysates were immunoprecipitated (IP) and western-blotted (WB) with the indicated antibodies. Scale bar: 20 µm.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development