ZFIN Image: Viringipurampeer et al., 2014, Fig. 6

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Figure Caption

Fig. 6

Phenotype at 4d.p.f. after morpholino knockdown of rip3 in wild-type (wt) and pde6c^w59 mutant (mt) embryos. (a–d) rip3 morpholino (MO) injection. (e–g) rip3 mismatch morpholino (MM) injection. (a and e) Control injections of MO or MM in wt embryos. Zpr1 cone-specific labelling in red. Scale bar=μm. (b) rip3 MO knockdown in mt embryos showing increased zpr1 labelling in red. (c) TUNEL labelling in rip3 MO knockdown mt embryos. (d) TUNEL labelling in mt embryos co-injected with rip3 MO and rip3 RNA. (f) rip3 MM knockdown in mt embryos showing decreased zpr1 labelling in red. (g) TUNEL labelling in mt embryos injected with rip3 MM. (h) ELISA quantitation of carbonyl content in wt, mt and MO-injected embryos at 4d.p.f. (white bars) or 7d.p.f. (black bars). Mean±S.E.M., n=8, *P<0.0001; **P<0.001

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

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