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Fig. S2
Western Analysis Showing MITF, IRF4, TFAP2A, and TYR Expression upon shRNA Treatment, Related to Figure 4C
Western blot showing expression of the MITF (Thermo Fisher C5), TFAP2A (Abcam ab52222), IRF4 (Cell Signaling, IRF4 (CST #4299), TYR (Santa Cruz sc-7833) and β-actin (Millipore C4 MAB1501R) proteins in 501mel cells after shRNA treatment.
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Reprinted from Cell, 155(5), Praetorius, C., Grill, C., Stacey, S.N., Metcalf, A.M., Gorkin, D.U., Robinson, K.C., Van Otterloo, E., Kim, R.S., Bergsteinsdottir, K., Ogmundsdottir, M.H., Magnusdottir, E., Mishra, P.J., Davis, S.R., Guo, T., Zaidi, M.R., Helgason, A.S., Sigurdsson, M.I., Meltzer, P.S., Merlino, G., Petit, V., Larue, L., Loftus, S.K., Adams, D.R., Sobhiafshar, U., Emre, N.C., Pavan, W.J., Cornell, R., Smith, A.G., McCallion, A.S., Fisher, D.E., Stefansson, K., Sturm, R.A., and Steingrimsson, E., A Polymorphism in IRF4 Affects Human Pigmentation through a Tyrosinase-Dependent MITF/TFAP2A Pathway, 1022-1033, Copyright (2013) with permission from Elsevier. Full text @ Cell