ZFIN Image: Rosenfeld et al., 2013, Fig. 4

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Figure Caption

Fig. 4

Hspb7 regulates ventricular cardiomyocyte size. (A) Representative phenotypes demonstrating the ventricular cell size observed in the indicated experimental conditions at 48 hpf in embryos derived from the myl7:actn3b; myl7:mKate-Caax reporter strain. The bars represent 10 μm. (B) Wildtype embryos (wt, n=3) or embryos injected with the standard control MO (control, n=4), hspb7 MO (hspb7, n=5), hspb12 MO (hspb12, n=3), or hspb7+12 MOs (hspb7+12, n=4) were evaluated with ImageJ to measure average cell area. At least seven cells were analyzed for each embryo to determine the average. The asterisk indicates p<0.05 by Student′s t-test in comparison to the standard control group.

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Acknowledgments

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Reprinted from Developmental Biology, 381(2), Rosenfeld, G.E., Mercer, E.J., Mason, C.E., and Evans, T., Small heat shock proteins Hspb7 and Hspb12 regulate early steps of cardiac morphogenesis, 389-400, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.