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Fig. 2
Notch invalidation triggers continuous overgrowth of the pallial GZ through RG amplification. (A-E) Cross-sections of the pallial ventricular zone following different length of LY411575 treatment (d, days of treatment) stained for the RG marker GFAP-GFP (green) and the proliferation marker MCM5 (magenta). (F) Percentage of RG in cycle (GFAP/MCM5 positive) during LY treatment. (G) Total number of RG (GFAP positive). **P<0.005; ***P<0.0001 (n=4 brains for each condition). Scale bars: 20 μm. Confocal projections of four optical planes (each 1 μm).
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