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Fig. S3
Time-lapse analyses of myelin sheath retractions
Relates to Figure 3 and Movies S4 and S5.
(A+B) Images from time-lapse analyses of Tg(mbp:EGFP-CAAX) animals showing myelin sheath retractions. In one example (A) the myelin sheath is retracted from an axon without myelin sheaths nearby, whereas in (B) the myelin sheath is being retracted from an axon that retains neighbouring myelin sheaths.
Scale bar=5μm.
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Reprinted from Developmental Cell, 25(6), Czopka, T., Ffrench-Constant, C., and Lyons, D.A., Individual Oligodendrocytes Have Only a Few Hours in which to Generate New Myelin Sheaths In Vivo, 599-609, Copyright (2013) with permission from Elsevier. Full text @ Dev. Cell