ZFIN Image: Catterson et al., 2013, Fig. 5

Image

Figure Caption

Fig. 5

Cardiomyocyte Fit2 compensates for the loss of Fit1 to establish the cardiac syncytium.

(A) Schematic showing the Fit1 locus with the adjacent genes (CG14995 and Ack) and the site of the P-element insertion used to create the 1.7 kb deletion mutant (Fit1^Δ161). (B) PCR of genomic DNA from wild-type (w¹¹¹⁸) and Fit1^Δ161 mutant flies. (C) Micrographs of adult hearts stained with phalloidin. The arrow highlights an abnormal cardiomyocyte phenotype. (D) Mean (±SEM) distance between neighbouring cardiomyocytes. n = 12–16 measurements from four to seven independent flies for each genotype. ***P<0.001 from all other genotypes. Legend applies to C & D.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One