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Figure Caption
Fig. S4 (related to Fig. 4) NPA increases motor neuron numbers and decreases V2 interneuron numbers in human ES cell cultures. A,B: At day 44, HB9+/βIII tubulin+ cells are present (A) and the percentage of HB9+ motor neurons (B) is increased (P = 0.0036) by NPA treatment. C,D: At day 26, FOXN4+/βIII tubulin+ interneurons are present in the cultures (C) and the percentage of FOXN4+ interneurons is decreased by NPA treatment (D; P < 0.05). Error bars represent SEM. Scale bars: 50 μm.
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Reprinted from Developmental Cell, 25(5), Reimer, M.M., Norris, A., Ohnmacht, J., Patani, R., Zhong, Z., Dias, T.B., Kuscha, V., Scott, A.L., Chen, Y.C., Rozov, S., Frazer, S.L., Wyatt, C., Higashijima, S., Patton, E.E., Panula, P., Chandran, S., Becker, T., and Becker, C.G., Dopamine from the Brain Promotes Spinal Motor Neuron Generation during Development and Adult Regeneration, 478-491, Copyright (2013) with permission from Elsevier. Full text @ Dev. Cell