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Fig. 1 Zebrafish Ptk7 structure and embryonic expression. (A) Domain structure of zebrafish Ptk7 and its homology to chicken (KLG), Xenopus, mouse and human orthologues. Numbers indicate percentage amino-acid identity within extracellular immunoglobulin (IG), transmembrane (TM) and intracellular pseudokinase (PK) domains. (B-F) WISH of ptk7 expression throughout the first 24 hours of development. Lateral views of two-cell (0.75 hpf, B), shield (6 hpf; C), bud (10 hpf; D), 10- to 12-somite (15 hpf; E) and 24 hpf (F) stage embryos are shown.
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