ZFIN Image: Kuo et al., 2013, Fig. 5

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Figure Caption

Fig. 5 Effects of FGF and Sox3 upon the expression of chd cannot be rescued by Gsc.

Injection of different mixtures of sox3 or gsc RNA resulted in a range of expression levels of chd from complete repression to dramatic ‘continuous’ expansion as shown in the right of panel A. The phenotypes seen when combinations of sox3 and gsc were injected, were intermediate between those when sox3 or gsc alone were injected (Shown in bar chart in panel A). Treatment with SU5402 was able to inhibit chd expression (Ba,b) even when 50 pg (Bc,d) or 100 pg (Be,f) gsc RNA was also injected. Shown in bar chart in panel C. The proportion of embryos exhibiting these phenotypes is shown at the bottom right of each panel.

Acknowledgments

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