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Figure Caption
Fig. 4 Microtubule disassembly inhibits PI(3)K activation at the leading edge. (A) Time-lapse ratiometric imaging (PHAKT-GFP/mCherry) of PI(3,4,5)P3?PI(3,4)P2 dynamics during neutrophil random motility in the head. (B) Microtubule depolymerization inhibits localization of PI(3,4,5)P3?PI(3,4)P2 at the leading edge. Scale bars: 10 μm.
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Full text @ J. Cell Sci.