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Figure Caption
Fig. S2 dgf-/- mutant embryos can be rescued by transgenic insertion of a BAC containing the enpp1 gene, and dgfsa156 encodes a mutation in enpp1. (A) BAC-rescued embryos exhibit a wild-type phenotype (shown in Fig. 3A). The SNP variant (arrow) is linked to the dgf mutation (sequence, Middle). (B) PCR indicating the presence of the enpp1 BAC in rescued dgf-/- embryos and its absence in nonrescued dgf-/- embryos. (C) Sequencing of the dgfsa156 allele, kindly provided by The Sanger Center, reveals an Arg427>stop in the enpp1 gene.
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