Fig. 9 Spatial distribution of zfdor2 at 24 and 48 hpf.
Lateral views (A-D, G-J), dorsal views (E-F, K-L). At 24 hpf, zfdor2 was found in the telencephalon, diencephalon, midbrain (optic tectum), MHB, hindbrain, spinal cord, eye and somites. At 48 hpf, zfdor2 was expressed to a similar extent as at 24 hpf, also with expression in the MLF, notochord, pectoral flipper and heart. Cocaine did not induce evident changes in the expression of zfdor2 at 24 hpf (except in the spinal cord, where its expression was increased (arrowhead), or at 48 hpf. Abbreviations: T: telencephalon; Mb: midbrain, Hb: hindbrain, D: diencephalon, N: notochord; SC: spinal cord; S: somite; pf: pectoral flipper; H: heart. Scale bar: 200 μm in A (Applies to B, G and H) and 250 μm in C (Applies to D, E, F, I, J, K and L).