Fig. 8 Spatial distribution of zfdor1 at 24 and 48 hpf.
Lateral views (A-D, G-J), dorsal views (E-F, K-L). zfdor1 was found in telencephalon, diencephalon, midbrain (optic tectum), MHB, hindbrain, spinal cord, eye and somites. Expression in embryos exposed to cocaine in the optic tectum (asterisk), telencephalon, midbrain, hindbrain and spinal. At 48 hpf zfdor1 was expressed to a similar extent as at 24 hpf, but also with expression in the MLF, notochord, pectoral flipper and heart. Cocaine induced a decrease in expression in the telencephalon and MLF (arrowhead and asterisk, respectively). Abbreviations: T: telencephalon; Mb: midbrain, Hb: hindbrain, D: diencephalon, N: notochord; SC: spinal cord; S: somite; pf: pectoral flipper; H: heart. Scale bar: 200 μm in A (Applies to B, G and H) and 250 μm in C (Applies to D, E, F, I, J, K and L).