IMAGE

Fig. 1

ID
ZDB-IMAGE-121212-23
Source
Figures for Lane et al., 2012
Image
Figure Caption

Fig. 1 Otx morpholino knockdown results in a variable degree of RPE deficits in zebrafish.

(A–B) Control morpholino (A) and otx1a/otx2 morpholino (B) injected embryos photographed at 35 hpf. RPE pigmentation is reduced in otx1a/otx2 morphants (black arrows) while neural crest derived melanocytes are unaffected (white arrows). (C–D) Ventral view of 5 dpf control morpholino (C) and otx1a/otx2 morpholino (D) injected larvae. The phenotype of otx1a/otx2 morphants can vary in severity between eyes of the same embryo, with one eye displaying a minor coloboma phenotype (black arrow) and the other eye displaying a major coloboma phenotype (white arrow).

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Acknowledgments
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