ZFIN Image: Hoffman et al., 2012, Fig. 3

Image

Figure Caption

Fig. 3 Quantification of lymphatic capillary development after knockdown with a vegfc morpholino.

Red fluorescent images from late-phase microangiograms of Tg(fli1:EGFP)^y1 zebrafish are shown, highlighting Texas Red-LMD uptake within lymphatic capillaries. Results of quantitative morphometric analyses are displayed in bar graphs. A and B, Zebrafish injected with a vegfc morpholino (MO) have significant inhibition of lymphatic capillary growth at 3 dpf (n = 32) compared to untreated zebrafish (n = 32) or those exposed to rhVEGF-C (n = 14), which is mitigated by the addition of rhVEGF-C (100 pg/ml) to the aqueous environment (n = 15). *P<0.0001, **P<0.0001. Scale bars, 50 μm.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One