ZFIN Image: Jao et al., 2012, Fig. 3

Image

Figure Caption

Fig. 3

Motoneuron phenotypes of gle1^–/– mutants. (A-D) Confocal images of live wild-type (A,C) and gle1^–/– (B,D) zebrafish embryos with motoneurons labeled by mnx1:GFP transgene at 54 hpf (A,B) and 78 hpf (C,D). Compared with wild-type siblings, gle1^–/– embryos have fewer motoneurons in the spinal cord (B, bracket), lack rostrally projecting axons (asterisks in wild type, A) around the horizontal myoseptum, and exhibit disorganized axon arbors and ectopic branching (B,D). The phenotypes are exacerbated with age. Images are lateral views of the trunk spinal cord with dorsal to top, anterior to left. Scale bars: 50 μm.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

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