ZFIN Image: Buck et al., 2012, Fig. 6

Image

Figure Caption

Fig. 6 The effects of copper sulphate and neomycin exposure on the ear and pLL of Tg(pou4f3::mGFP) larvae. Treatment with neomycin and copper sulphate (E–H) did not affect GFP expression in the hair cells of the inner ear when compared to control treatment (A–D). These images were taken at both the anterior and posterior focal planes in live animals. A, anterior macula; P, posterior macula; arrowheads indicate the cristae of the semicircular canals. Scale bar = 200 μm. Treatment with neomycin (K) but not copper sulphate (L) caused a strong decrease in GFP expression in hair cells of the pLL, when compared to control treatment (I and J). Scale bar = 500 μm. Images are representative of an n of 12 per treatment group.

Acknowledgments

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Reprinted from Hearing Research, 284(1-2), Buck, L.M., Winter, M.J., Redfern, W.S., and Whitfield, T.T., Ototoxin-induced cellular damage in neuromasts disrupts lateral line function in larval zebrafish, 67-81, Copyright (2012) with permission from Elsevier. Full text @ Hear. Res.