ZFIN Image: McKeown et al., 2012, Fig. 5

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Figure Caption

Fig. 5

slc1a2b exhibits dynamic expression in the hindbrain and spinal cord across development. Lateral (A,C,E,G) and dorsal views (B,D,F,H) are shown, with the brackets indicating the regions shown at higher magnification in the insets. For orientation in dorsal images, the arrows indicate the location of the otic placode. (A,B) At 19 hpf, slc1a2b shows robust expression in rhombomere 4 of the hindbrain with punctate, less pronounced expression in the spinal cord. (C,D) At 24 hpf, slc1a2b expression continues to expand throughout the hindbrain and caudally into the spinal cord compared to 19 hpf. (E,F) At 48 hpf, slc1a2b is expressed in the hindbrain and in the spinal cord. (G,H) At 96 hpf, slc1a2b is widely expressed in the hindbrain and spinal cord, other brain regions, and in the retina.

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Acknowledgments

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Reprinted from Developmental Biology, 362(2), McKeown, K.A., Moreno, R., Hall, V.L., Ribera, A.B., and Downes, G.B., Disruption of Eaat2b, a glutamate transporter, results in abnormal motor behaviors in developing zebrafish, 162-171, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.