ZFIN Image: Zhang et al., 2012, Fig. S4

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Figure Caption

Fig. S4

Deficiencies of both dkc1 and nola1 lead to the defects of rRNA processing. (A) Schematic figure modified from previous report [29] shows the overview of rRNA processing. (B) A significant decrease of a precursor strand generating ITS1 and 18 S rRNA was detected in the lanes probed with ITS1 in both dkc1 morphant and nola1 mutant compared with wild type controls (arrows in a and b). The total amount of 18 S rRNA was reduced significantly as shown in the lanes probed with 18 S rRNA probe. The intensity of staining of 18 S rRNA relative to the background was measured using ImageJ program. In contrast, no obvious difference was detected in the lanes probed with ITS2 probe.

Acknowledgments

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