ZFIN Image: Hochmann et al., 2012, Fig. 5

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Figure Caption

Fig. 5

Retinal pigment epithelium is expanded following Fgf signaling inhibition.

A) After one day of heat shock treatment control siblings do not show any change in the RPE structure. B) In transgenic siblings, RPE cells appear more stretched, reaching out to the outer segments of the photoreceptor cells (black arrow). A2, B2) At higher magnification, the RPE contacts photoreceptor cells in the POS in the transgenic fish (arrow), while this was not detected in retinas of control fish. C) The black error bar indicates the width of the RPE in control siblings. D) In contrast, the width of the RPE is highly increased (white error bar) in retinas of dn-fgfr1 fish after two days of heat shock treatment. Scale bars = 20 μm.

Acknowledgments

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