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Fig. 4 The effect of LMWF on hair regeneration after neomycin-induced ototoxicity in POU4f3::GFP larvae. (A) A greater number of hair cells was observed in the neuromasts (P8) of LWMF-treated larvae 12 h after neomycin treatment. (B) Summarized data from six independent experiments. LMWF (50 μg/ml) significantly enhanced hair cell regeneration 12 and 16 h after neomycin treatment. (C) Concentrations of LMWF above 50 μg/ml had similar effects on hair cell regeneration (p < 0.001 compared to neomycin only).
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Reprinted from Hearing Research, 282(1-2), Moon, I.S., So, J.H., Jung, Y.M., Lee, W.S., Kim, E.Y., Kim, C.H., and Choi, J.Y., Fucoidan promotes mechanosensory hair cell regeneration following amino glycoside-induced cell death, 236-42, Copyright (2011) with permission from Elsevier. Full text @ Hear. Res.