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Fig. 3
crb embryos exhibit abnormal mitoses and genomic instability. (A) Mitotic cells shown stained with DAPI (blue), α-tubulin (red), and γ-tubulin (green). (B) DNA content of crb (red) and wild-type (blue) embryos as measured by flow cytometry. (C) Metaphase chromosome spreads from a diploid cell containing 50 chromosomes (Left) and a crb hypertetraploid cell containing 108 chromosomes (Right). (D) FISH analysis on crb mutant embryos with probes for linkage group 2 (red) and linkage group 16 (green) and DAPI counterstaining.
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Full text @ Proc. Natl. Acad. Sci. USA