Fig. 3
Msw allele randomize Nodal pathway.
A, From left to right, dorsal view of left-sided, bilateral and right-sided expression of lefty1 in the dorsal diencephalon detected in 22 somite-stage embryos. B, Percentages of normal (left-sided), bilateral and reversed lefty1 in WT control (n = 44), embryos from msw+/+ females (n = 33), embryos from msw+/- females (n = 435) and from msw-/- females (n = 403). C, spaw expression in the dorsal diencephalon in 15–18 somite-stage embryos. From left to right, dorsal view showing normal (left-sided), bilateral and right-sided expression. D, Percentages of normal (left-sided), bilateral and reversed spaw in WT control (n = 169), msw+/+ females (n = 126), embryos from msw+/- females (n = 203) and from msw-/- females (n = 753).