ZFIN Image: Huang et al., 2011, Fig. 5

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Figure Caption

Fig. 5

Rescuing effect of mevalonate on the shortened sarcomere induced with statin.

Left: the control, untreated zebrafish; middle: zebrafish subject to a treatment of statin (0.5 μM) at 24 hpf for 12 h; right: zebrafish subject to a co-treatment of statin (0.5 μM) and mevalonate (100 μM) at 24 hpf for 12 h. All SHG images used to determine the sarcomere length were measured at 36 hpf on somites near the head (black, somites 5~8) and the tail (red, somites 21–24). The two images displayed as insets are representative results of co-treatment measured near the head (left) and the tail (right), respectively. Image size: 50×50 μm. The statistics were calculated based on 21 images obtained from three zebrafish.

Acknowledgments

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