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Fig. 2
Effect of HIF-1α mRNA over-expression on PGC migration in zebrafish embryos.
(A) Embryos injected with GFP-nosl 32UTR mRNA. (B) Embryos co-injected with GFP-nosl 32UTR mRNA and HIF-1α mRNA. HIF-1α over-expressed embryos showed mis-migrated ectopic PGCs in the head, yolk sac extension and caudal region. HIF-1α over-expressed embryos displayed similar phenotypes as embryos exposed to hypoxia. Scale bar: 200 μm.
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