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Fig. S9

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Publication: Matsui et al., 2011 - Canopy1, a positive feedback regulator of FGF signaling, controls progenitor cell clustering during Kupffer's vesicle organogenesis
All Figures: Figures for Matsui et al., 2011

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Fig. S9

DFC-specific knockdown of cnpy1 attenuates F-actin accumulation at the cell-cell contact sites of DFCs. (A, B) Distribution of F-actin (red) and FITC-labeled MO (green) in DFC^control-MO (A) or DFC^cnpy1-MO (B) embryos. Dorsal view, anterior to the top. Scale bar: 20 μm. White dotted lines mark the plasma membrane outlines of MO-containing DFC populations. (A’, B’) Higher-magnification images highlight MO-containing DFCs. In control-MO-containing DFCs (A’), F-actin accumulated at the cell-cell contact sites of the plasma membrane. However, accumulation of F-actin was limited in cnpy1-MO-containing DFCs (B’).

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