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Fig. S3
The Cxcl12 30s loop is crucial for receptor affinity and activation. (A-E) Receptor internalization of Cxcr4b as a measure of Cxcl12 activity in vitro. Representative confocal images of HEK293T-Cxcr4b-YPet cells after incubation with conditioned medium containing the different Cxcl12 versions.
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