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Figure Caption
Fig. s5
Time course of top2b expression. Top row shows noto clutch embryos and larvae stained with top2b antisense probe. Bottom rows shows higher power images of single fish. (A,D) top2b is expressed ubiquitously at 1 dpf. (B,E) By 2 dpf, expression is restricted to the eyes, head and trunk. Inset in E shows a coronal section showing broad expression in eye and brain. (C,F) By 6 dpf, expression appears to be restricted to the eye and brain. Scale bar: 1 mm in A; 1.2 mm in B,C; 400 μm in D; 100 μm in E,F; 120 μm in E (inset).
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