ZFIN Image: Yin et al., 2011, Fig. S1

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Figure Caption

Fig. S1 Dosage-dependent effect of IWR-1 on specification of the swimbladder epithelial cells. The Et(krt4:EGFP)^sq33-2 embryos were cultured in egg water with IWR-1 addition from 12 hpf at a concentration as indicated, and was live-imaged for GFP fluorescence at 72 hpf. (A) Fully developed epithelium of the swimbladder at 72 hpf in a control embryo. (B, C) The small bud of the swimbladder epithelium in embryos treated with 1 μM (B) and 5 µM (C) IWR-1. (D, E) The absence of the swimbladder epithelium at 72 hpf in embryos treated with 10 μM (D) and 20 μM (E) IWR-1. Dotted circles indicate the position of swimbladder. Abbreviations: sb, swimbladder.

Acknowledgments

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