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Fig. S2 Histology of melanoma. a–c) H&E staining of representative tail regions of kita-GFP-RAS fish at the ages indicated. d–e) Representative electromicrographs of a hyperpigmented (d) and a hypopigmented (e) melanoma. f) in situ hybridization for dopachromo tautomerasis (dct) in a cryostat section of a tail hypopigmented melanoma from a 1 month old transgenic zebrafish. Calibration bars = 100 μm for a,b,c,f; 0.5 mm for d and e.
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