ZFIN Image: Cao et al., 2009, Fig. S4

Image

Figure Caption

Fig. S4 Comparison of phenotypes caused by hdac1 depletion and VPA and TSA treatment. (A) Stunted pectoral fin (blue arrow) development on 3 dpf in a hdac1/hi1618 mutant embryo (1618), a wild-type embryo treated with 300 nM TSA (TSA), 20 μM VPA (VPA), and 50 μm (VPM) from the 30% epiboly stage. (B) Pericardiac edema (red arrow) on 3 dpf in a hdac1/hi1618 mutant embryo. WT: wild-type sibling. mut: hdac1/hi1618 mutant. (C) Treatment of 300 nM TSA from the 30% epiboly stage leads to pericardiac edema (red arrow) on 3 dpf, while similar treatment with 50 μM VPM does not. (D) Treatment of 20 μM TSA from the 30% epiboly stage leads to pericardiac edema (red arrow) on 3 dpf.

Acknowledgments

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