ZFIN Image: Dahl Ejby Jensen et al., 2009, Fig. 4

Image

Figure Caption

Fig. 4 Hypoxia-induced lymphatic perfusion is dependent on NO. (A) Tailfin lymphatic perfusion under normoxia. (Scale bar, 50 μm.) (B) Tailfin lymphatic perfusion under normoxia in zebrafish treated with 100 μM sodium nitroprusside (SNP). Under hypoxic conditions, tailfin lymphatic perfusion of (C) control zebrafish (vehicle), and zebrafish treated with (D) 1 μM l-NMMA, (E) 1 μM ODQ, (F) 10 μM c-PTIO, (G) 1 μM l-NMMA + 100 μM SNP, and (H) 1 μM ODQ + 100 μM SNP. Dashed blue lines mark the border of the lymphatics, and red dots indicate blood cells. (I) Quantification of blood cells in tailfin lymphatics under different conditions. ***, P < 0.001; NS, not significant.

Acknowledgments

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