IMAGE

Fig. S4

ID
ZDB-IMAGE-101115-36
Source
Figures for Scholpp et al., 2009
Image
Figure Caption

Fig. S4 Neurog1 represses GABAergic cell fate. Mis-expression of neurog1 mRNA leads to a strong down-regulation of ascl1a expression at 28 hpf (a and b) and a down-regulation of the expression of gad1 at 32 hpf (c and d). neurog1 mRNA over-expression leads gross changes in head morphology such as the lack of optic vesicle formation. Clonally over-expression of neurog1 mRNA leads to the cell-autonomous down-regulation of shh:GFP within the MDO and tal1:GFP within the rTh (32/45; f and h; arrowheads). Control cells carrying the lineage tracer rhodamine dextran only show co-localization with the GFP markers (e and g; arrowheads). cTh, caudal thalamus; MDO, mid-diencephalic organizer; PTh, prethalamus; PTec, pretectum.

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA
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