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Fig. S3 Consistent perturbations of gene expression patterns result from MO-induced depletion of Ship2a protein in zebrafish embryos. Representative groups of WT (A,C,E) or Ship2a-depleted (B,D,F) pre-gastrula embryos. Within each group, stage-specific gene expression patterns are highly reproducible. bmp4 and eve1, genes that are expressed at higher levels on the ventral side of the WT embryo, are downregulated in ship2a morphants. mkp3, a dorsal-specific marker in WT embryos, is expressed throughout the blastoderm margin in ship2a morphants.
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Full text @ Dis. Model. Mech.