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Fig. 3 BT10 added during early embryogenesis causes a major disruption of the body axis.
Shown are representative embryos (from 3 experiments, for each sample n = 20) treated with BT10 at 10 μM (A-D) compared to embryos treated only with vehicle (DMSO) as control. BT10 was added at 5 hpf (A, B) or 8 hpf (C, D). DMSO alone was added at 5 hpf (E, F). Embryos were allowed to develop until 24 hpf (A, C, E) or 48 hpf (B, D, F). The position of the yolk is indicated in panels A and B. All embryos are viewed laterally, anterior to the right, dorsal at the top.
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