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Figure Caption
Fig. 1 meis1-morphant embryos fail to produce visible circulating erythrocytes. (A, B) Lateral view of live 48 hpf embryos showing close-up of heart region; anterior to the left. Unlike their wild type (WT) counterparts (A), meis1-morphant (B) embryos lack visible circulating blood cells. Arrows indicate heart. (C, D) o-dianisidine staining of differentiated erythrocytes in 48 hpf whole-mount embryos; ventral view with anterior to the left. o-dianisidine staining is abolished in meis1-morphant (D) embryos when compared to WT embryos (C).
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Reprinted from Developmental Biology, 340(2), Pillay, L.M., Forrester, A.M., Erickson, T., Berman, J.N., and Waskiewicz, A.J., The Hox cofactors Meis1 and Pbx act upstream of gata1 to regulate primitive hematopoiesis, 306-317, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.