ZFIN Image: Olesnicky Killian et al., 2009, Fig. 3

Image

Figure Caption

Fig. 3 cxcr4a morphants have neurocranium defects. Dorsal views, anterior to the top (A–C) and lateral views, anterior to the left (D, E). (A) wild type (WT) neurocranium at 6.5 dpf. (B) cxcr4a morphants lack an ethmoid plate (ep) and have fused trabeculae (t). (C) sdf1b morphants phenocopy cxcr4a morphants, and have more severe anterior basicapsular commissure defects (arrow). (D, E) Wildtype (D) and cxcr4a morphant embryo (E) labeled with anti HuC/D 52 hpf to indicate the cranial ganglia. Morphant embryos have a reduction in cranial ganglia IX and X (arrow). bc, basicapsular commissure; bp, basil plate; oa, occipital arch; ep, ethmoid plate; t, trabeculae.

Acknowledgments

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Reprinted from Developmental Biology, 333(1), Olesnicky Killian, E.C., Birkholz, D.A., and Artinger, K.B., A role for chemokine signaling in neural crest cell migration and craniofacial development, 161-172, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.