ZFIN Image: Mich et al., 2009, Fig. S3

Image

Figure Caption

Fig. S3 PGC migration is not perturbed in Hh pathway mutants or morphants. (A–E) PGCs are localized to the presumptive gonad in syu^tbx392, con^tm15a, smu^hi1640, yot^ty119, and dts^ts269 mutant zebrafish, as indicated by the distribution of vasa-expressing cells. (F) Embryos co-injected with smo MO (6 ng/embryo) and EGFP-nanos1-3′UTR RNA (100 pg/embryo) also exhibit properly localized PGCs (arrows). 24-hpf (A–D, F) and 6-dpf (E) zebrafish are shown. Scale bars: 200 μm.

Acknowledgments

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Reprinted from Developmental Biology, 328(2), Mich, J.K., Blaser, H., Thomas, N.A., Firestone, A.J., Yelon, D., Raz, E., and Chen, J.K., Germ cell migration in zebrafish is cyclopamine-sensitive but Smoothened-independent, 342-354, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.