ZFIN Image: Goldstein et al., 1998, Fig. 1

Image

Figure Caption

Fig. 1 Relationship of Nkx2.5 expression and the anterior notochord. Whole mount in situ hybridization was performed on embryos fixed at the stages shown, and labeled with antisense probes for Nkx2.5 and ntl. Bilateral expression of Nkx2.5 is evident at the 6-somite stage. At the 14-somite stage the Nkx2.5 domain is more medially positioned (black arrow), and expression in its posterior extent (white arrow), that portion lateral to anterior notochord, is diminishing. At 18-somite stage, the caudal ends of the bilateral tubes begin to fuse just anterior to the notochord tip. Fusion is complete by the 22-somite stage, appearing as a ring anterior to the notochord.

Acknowledgments

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Reprinted from Developmental Biology, 201, Goldstein, A.M. and Fishman, M.C., Notochord regulates cardiac lineage in zebrafish embryos, 247-252, Copyright (1998) with permission from Elsevier. Full text @ Dev. Biol.